Gout arthritis is not life-threatening. But if the disease caused by high levels of uric acid in the blood had a chance to attack, people with disabilities can experience hand and foot joints. In order not to teridap, soto innards and his friends need to be avoided.
Midnight Blue was suddenly awakened. Because of garanya his right big toe joint pain and stiffness. The skin over the joints appeared swollen redness. First-time youth are in their 20s feel that way about her experience.
From the results of blood tests were known, the blood uric acid levels increased to 9 mg%. Normally, uric acid levels less than 7 mg%. Investigate the culprits turned out to have calibaration kedoyanan Iwan on foods containing high levels of purine, such as beef offal soup, lamb satay, fried lungs, etc.. Type of food as it is easy to increase levels of uric acid in the blood. In the end, Iwan also suffered from the interruption, which in medicine is called gout arthritis.
Uric acid or uric acid is an end nucleic acid or purine metabolism of substances (one of the elements of protein) in the cell body. Uric acid is carried to the kidneys via the bloodstream to be issued with urine. Healthy kidneys will regulate uric acid levels in the blood to keep it within normal levels. However, excessive uric acid will not be collected and processed entirely by the body. The advantages that eventually accumulate in the joints and tissues.
Uric acid, in limited numbers, are also produced from digested food. These acids via colon bacteria will be destroyed to be removed with a chemical that stool.
Excessive production of uric acid (hyperuricaemia) at high risk of several disorders such as arthritis gout, kidney stones, kidney damage and high blood pressure. Disorders gout arthritis is one type of arthritis (no more than 150 types of arthritis). Metabolic disorder is mostly attacking the joints or a single peripheral.
cacatGejala acute pain and stiffness to first attack the joints of my toes (bunion joint) to the other fingers. On stage further, can be up to his ankles, knees, elbows, and other small joints of the hands. Torment of pain and swelling are often causing the patient is difficult to walk. In fact, sometimes accompanied by fever and inflammation in the area of swollen joints was hot. Suffering may last 24-36 hours. In fact, could be much longer depending on the severity of inflammation.
However, acute attacks of gout arthritis does not always have to be in a state of high uric acid. Fluctuating levels of uric acid that tends to fall-rise, also can cause acute attacks. For example, a person with normal uric acid levels can be affected by an acute attack several hours after eating a bowl of soup beef offal. You see, this soup cause uric acid levels rise abruptly. Conversely, a person with high uric acid levels can have an acute attack if a diet is too strict or uric acid-lowering medication (allopurinol) high dose. A strict diet or consumption of these drugs cause uric acid levels dropped dramatically (below 5 mg%).
"Most appropriate, uric acid levels are not reduced dramatically, but slowly," said dr. Caecilia R. Padang, Ph.D., FACR, Rheumatology consultant from the Center for Rheumatic Indonesia, Jakarta. After the first attack, suggestions Caecilia, uric acid levels should continue to be monitored. If it gets a second attack, subsequent acute attacks would be more likely to occur, even prolonged and chronic.
Apart from food, alcohol (including tape and palm wine), and certain drugs such as medication is high blood pressure diuretic (increase urine production and mineral), or a small dose of aspirin in the long term to prevent heart attacks, could be inflated levels uric acid. "Indeed, both types of drugs are often a trigger in patients with gout potential. However, this rarely occurs in individuals who do not have the talent gout," said Caecilia, who obtained his doctorate in Australia.
Do not delay
Caecilia added, if uric acid levels in the blood for too long is left on top of 7 mg%, monosodium uric crystals (MSU) will accumulate in the joints and tissues. Collection of these crystals eventually form a lump under the skin, which then form tophi. When the MSU crystal deposition occurs in the kidneys, can cause kidney stones, can even damage the kidney tissue, which is feared will lead to kidney failure.
To reduce the risk of renal impairment, in addition to uric acid levels continue to be monitored and treated, it is recommended that patients drink lots of water (1-2 l per day or 3-4 l in summer). Color and clear urine can be to assess whether or not enough water consumption. Especially when I wake in the morning, the first urine color usually older and less clear. After that, the color of urine should be clear.
Tophi have different sizes. Small or microtophi only be seen through a microscope. Large easily seen and felt. Tophi a growing cause of disability: joint protruding legs or hands and become stiff.
In order not to become tophi, suggestions Caecilia, gout sufferers should continue to monitor the disease. First of all to eliminate inflammation, given anti-inflammatory drug (NSAID = non-steroidal anti-inflammatory drugs) or colchicine which has been known for more than 1,500 years to treat inflammation. These drugs show results within two days. Furthermore, given uric acid lowering drugs allopurinol and probenecid for 6 months - 2 years in limited doses. Tophi severe need of treatment for five years or more. There are times when patients are advised to drink the blood uric acid-lowering drugs for life if acute gout attacks occur more than five times a year. Or, the patient has suffered or is suffering from tophi and kidney stones.
Caecilia reminder for gout arthritis sufferers do not ever try to treat themselves by buying OTC drugs without a prescription. "Many cases are fatal because of too often take painkillers or eliminating inflammation," he said.
With allopurinol, the patient can not be cured in one treatment. Often still accompanied by acute attacks several times. You see, after the uric crystals in the joints is sucked out, still continued depletion of uric crystals that accumulate in tissues. This can cause arthritis back due to the release of foreign objects. "Often people stop drinking when the attack remains allupurinol arise after drinking a few times. They think the drug is no usefulness," said dr. Caecilia. "So now the drug is combined with drugs to prevent attacks until stable levels of uric acid."
Corticosteroid drugs like prednisone or prednisdolone also often used to treat gout arthritis. However, this drug is not recommended for long-term treatment.
More men
In Indonesia, the disease gout arthritis was first investigated by a Dutch doctor, dr. van den Horst, in 1935. At that time, he found 15 cases of severe gout in underprivileged communities in Java. The results in 1988 by dr. John Darmawan at Bandungan, Central Java, shows, among 4683 people aged 15-45 years are studied, 0.8% suffering from high uric acid (1.7% of men and 0.05% of women among them has reached the stage of gout .)
Early in the 90's, Prof.. Dr. E. Tehupedori has examined the possibility of differences in uric acid levels in certain ethnic longer significant. Apparently not! However found, 50% of people in town came for a treatment after 6.5 years suffering from gout, even 7-9 years later when the situation is more severe (suffering from gout tophikronik).
Caecilia himself had examined his homeland, North Sulawesi, where the risk factors for gout arthritis is quite high, especially in rural areas. Once the "familiar" of his people in there with this disease so that gout arthritis is considered a hereditary disease. "As a result, they are less ignored the early symptoms and the average new treatment came after suffering disability due to chronic gout tophi," he said. Though the main risk factors, according to medical experts this rheumatic disease, most likely from their diets daily familial.
Also revealed, in Indonesia suffered gout arthritis at earlier age than in Western countries. In Indonesia 32% of gout attacks occur in men under 34 years of age. While abroad on average suffered by men above that age.
In those who drank alcohol every day of the traditional (wine or tape), by Caecilia, gout risk factor to 50%. In those who drink alcohol more than once a week 40% risk factor. Similarly, their daily habits to eat seafood (shrimp, crab, oysters, mussels), offal, thick broth (soup), meat dogs, bats, and goats.
Families that have a positive history of gout, according Caecilia, 60% of family members affected by gout attacks, and nearly 47.4% of them men. Obese men have a higher tendency than the lean. In contrast, fewer suffered gout in children or women under the age of menopause.
Gout disease is often accompanied by high blood pressure (22%) and kidney stones (13%). At times, gout is also a trigger of coronary heart disease and diabetes mellitus or diabetes. Approximately 86% of renal impairment was found in patients with gout arthritis in Minahasa. However, it is not clear whether the kidney disorder causing elevated uric acid levels or vice versa. It should also be tested whether high blood pressure is difficult to go down was also related to renal factors. Thus, the occurrence of risk factors for gout arthritis can be a family history, diet, obesity, and kidney disorders.
It is time for education about prevention and treatment of gout arthritis disseminated to the rural corners. "Power paramedical health centers can help provide an explanation about the disease and follow up, either from diet or treatment," said Caecilia. "Information by using the booklet seems to have not been caught, and uric acid-lowering drugs was not disseminated to the health center."
If the first gout arthritis disease only affects men say the middle class and above, recent research shows, the disease knows no class.
Once caught the disease, one must pay attention to life imprisonment. By studying the history of family illness, manage your diet, be diligent to control and treat regularly, arthritis, gout will experience a period of remission. That is, if uric acid is maintained at normal levels, gout attacks should not be repeated again. (susukolostrum)
See also: sushi, wine
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